Basal ganglia output reflects internally-specified movements

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Basal ganglia output reflects internally-specified movements

How movements are selected is a fundamental question in systems neuroscience. While many studies have elucidated the sensorimotor transformations underlying stimulus-guided movements, less is known about how internal goals - critical drivers of goal-directed behavior - guide movements. The basal ganglia are known to bias movement selection according to value, one form of internal goal. Here, we...

متن کامل

GABAergic output of the basal ganglia.

Using GABAergic outputs from the SNr or GP(i), the basal ganglia exert inhibitory control over several motor areas in the brainstem which in turn control the central pattern generators for the basic motor repertoire including eye-head orientation, locomotion, mouth movements, and vocalization. These movements are by default kept suppressed by tonic rapid firing of SNr/GP(i) neurons, but can be ...

متن کامل

Multiple output channels in the basal ganglia.

The neural circuits that link the basal ganglia with the cerebral cortex are critically involved in the generation and control of voluntary movement. Retrograde transneuronal transport of herpes simplex virus type 1 was used to examine the organization of connections in the cebus monkey between an output nucleus of the basal ganglia, the internal segment of the globus pallidus (GPi), and three ...

متن کامل

Basal Ganglia Output Controls Active Avoidance Behavior.

Engrained avoidance behavior is highly adaptive when it keeps away harmful events and can be highly maladaptive when individuals elude harmless situations in anxiety disorders, but the neural circuits that mediate avoidance are poorly understood. Using DREADDs and optogenetics in mice, we show that the output of the basal ganglia through the substantia nigra pars reticulata (SNr) controls activ...

متن کامل

THE BASAL GANGLIA CIRCUITRY Proper execution of voluntary movements

Parkinson’s disease (PD) is a progressive, neurodegenerative disorder, in which the capacity to execute voluntary movements is gradually lost. The clinical picture of PD includes t r e m o r, rigidity and bradykinesia. The pathologic hallmark of the disease is the degeneration of melanine-containing, dopaminerg i c neurons of the substantia nigra pars compacta, which leads to severe dopaminergi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: eLife

سال: 2016

ISSN: 2050-084X

DOI: 10.7554/elife.13833